Role of Toll like receptor 4 and interleukine-1A polymorphisms in Generalized Aggressive Periodontitis in a Romanian Population
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Toll-Like Receptor 2 Gene Polymorphisms Associated with Aggressive Periodontitis in Japanese
BACKGROUND AND OBJECTIVE Aggressive periodontitis is a rare and very severe periodontal disease of early onset, which is closely associated with Porphyromonas.gingivalis (P.g.) infection in the Japanese population. TLR2 encodes Toll-like receptor 2, which plays an important role in the protective response to P.g. infection. We investigated a possible association between TLR2 and aggressive peri...
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Objective(s): This study was aimed to evaluate whether single nucleotide polymorphisms (SNPs) of TLR4 and common living habits of prostate hyperplasia (BPH) patients would affect the subjects’ risk and prognosis.Materials and Methods: We totally recruited 501 BPH patients and 964 healthy controls. The patients’ international prostate symptom score (IPSS) and quality of life assessment (QoL) wer...
متن کاملDetection of IL-4, IL-6 and IL-12 Serum Levels in Generalized Aggressive Periodontitis
Background: Periodontitis is a multifactorial chronic inflammatory disease characterized by destruction of tooth-supporting tissues. Environmental and genetic factors as well as the immune system participate in this process. Recent studies have attempted to elucidate the role of cytokine networks involved in periodontal diseases. Objective: To assess and compare the levels of IL-4, IL-6 and IL-...
متن کاملارتباط پلی‌مورفیسم‌های ژنتیکی پذیرنده شبه Toll 4 (TLR4) و استعداد ابتلا به سل ریوی
Background & Aim: Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4) are the members of the Toll-like receptor family and play important roles in recognition and subsequent immune response against mycobacteria. Two functional polymorphisms for TLR2 (Arg677Trp, C à T Arg753Gln, G à A) and TLR4 (Asp299Gly, A à G Thr399Ile, C à T) genes have been associated with a negative influence on ...
متن کاملP-225: Gene Variations of Toll-Like Receptor 3 in Endometriosis
Background: Endometriosis is a common gynecologic disorder that is characterized by the ectopic growth of endometrial tissue. Recently, endometriosis has been alternatively described as an immune, genetic and hormonal disease caused by exposure to environmental factors. Toll-like receptor 3 (TLR3) comprises a family of receptors through directly recognizing exogenous and endogenous ligands play...
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تاریخ انتشار 2014